Seven signs your stomachache could be serious
Medically reviewed by Dr. Betsy Koickel, MD on December 16th 2025.
Stomach aches are a common symptom experienced by adults and children alike for a variety of reasons. Most stomach aches are non-serious, caused by issues including indigestion, food intolerance, gas pain or stress. However, in some cases, stomach aches can be a sign that something more serious is going on.
Here are seven signs your stomach ache may be serious and require immediate medical attention.
Sudden & intense abdominal pain
A stomach ache that happens gradually and causes mild discomfort is typically not serious. But abdominal pain that is sudden and severe can indicate that something is seriously wrong. A very severe and sudden abdominal stomach ache can be a sign of appendicitis, gallstones, a perforated intestine or, in rare cases, a rupturing abdominal aortic aneurysm.
If the pain is accompanied by nausea, vomiting or you are unable to stand up straight, go to the emergency room immediately
Accompanied by fever
Abdominal pain with a fever is often an indication of an infection, such as appendicitis, diverticulitis (an infection in the large intestine), cholecystitis (an infection in the gallbladder) or pyelonephritis (an infection in the kidneys).
If you have abdominal pain with a fever, it’s important to seek immediate medical attention to rule out these serious medical conditions. Left untreated, infections in the abdomen can quickly become serious or spread, so timely evaluation is critical.
Experiencing abdominal pain during pregnancy
In early pregnancy, abdominal pain can indicate an ectopic pregnancy, where the embryo implants in the fallopian tube instead of in the uterus. In later stages of pregnancy, abdominal pain can indicate early labor.
Cramping or pain accompanied by vaginal bleeding or dizziness can indicate an emergency. If you are (or think you might be) pregnant, it’s important to seek immediate medical care if you’re experiencing any pain.
Presence of vomiting and/or diarrhea
Vomiting and diarrhea can indicate a foodborne illness or other potentially serious causes of abdominal pain. Uncontrolled vomiting and diarrhea can also lead to dehydration. If vomiting or diarrhea lasts more than 24 hours, contains blood or is accompanied by fever or severe pain, seek emergency care.
Localized pain in a specific area
If you can point to where you have pain, it’s more likely to be a serious abdominal issue than if you’re experiencing a generalized stomachache. Pain that worsens with movement or touch can signal inflammation or infection in that region. If you have significant abdominal pain in a localized area, it’s important to be evaluated to rule out potentially serious causes of your symptoms.
Inability to find a comfortable position
Abdominal pain that’s so significant you can’t lie down, sit up, stand or walk without causing more discomfort can indicate a serious problem. If you’re experiencing abdominal pain and can’t find a comfortable position, seek immediate medical care.
Experiencing dizziness or shortness of breath
Abdominal pain accompanied by other symptoms, including dizziness or shortness of breath, can indicate that there’s a more serious underlying problem. These symptoms may suggest internal bleeding, dehydration or circulatory issues requiring immediate evaluation. If you’re experiencing abdominal pain accompanied by these symptoms, it’s a sign that you need to receive urgent medical attention.
When to visit urgent care for stomach pain
If the pain is sudden, severe or is paired with dizziness, chest pain or fainting, go to the emergency room. If your stomach pain is moderate, you can visit urgent care. They can also help with stomach pain accompanied by symptoms like nausea, vomiting, mild fever or diarrhea that doesn’t improve within a day or two.
Urgent care can help evaluate possible causes such as infections, food poisoning or early appendicitis before they worsen. To get started, find the center nearest you and walk in or save your spot online.
FAQs
Here are some frequently asked questions about stomach pain and stomach aches.
How to differentiate between a mild stomach ache and serious abdominal pain?
Mild stomach aches usually improve on their own and are often related to digestion or gas, while severe or persistent pain can signal a more serious condition requiring medical attention.
What are effective stomach ache remedies for mild discomfort?
Rest, hydration, gentle movement and bland foods like bananas, rice or toast can help ease mild stomach discomfort.
When should I seek medical care for stomach pain and stomach ache?
Seek medical care if the pain is severe, lasts more than a few hours or is accompanied by symptoms like fever, vomiting or dizziness.
What does a sudden and severe stomach ache indicate?
Sudden, intense abdominal pain can indicate conditions such as appendicitis, gallstones or a perforated organ and requires immediate evaluation.
How does fever relate to stomach ache and pain?
A fever with stomach pain often points to infection or inflammation, such as appendicitis, diverticulitis or gallbladder infection.
Sources:
https://www.medicalnewstoday.com/articles/318286.php
https://www.mayoclinic.org/symptoms/abdominal-pain/basics/causes/sym-20050728
